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Apexbio Technology LLC Dipotassium glycyrrhizinate 68797-35-3 5mg
Supplier: Apexbio Technology LLC A89765
Dipotassium glycyrrhizinate (CAS 68797-35-3) is a small-molecule inhibitor targeting high mobility group box 1 (HMGB1) protein-related signaling pathways It is designed to suppress HMGB1-associated inflammatory signaling cascades thereby reducing pro-inflammatory cytokine synthesis and transcriptional activation during inflammation Dipotassium glycyrrhizinate exerts its biological activity primarily through inhibition of HMGB1-mediated pathways In experimental models of allergic dermatitis dipotassium glycyrrhizinate demonstrates inhibitory activity with an IC50 value in the range of approximately 150 300 M depending on specific experimental conditions Based on these pharmacological properties dipotassium glycyrrhizinate holds research potential in biomedical studies of allergic inflammatory responses and the investigation of HMGB1-mediated inflammatory signaling
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