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Cayman Chemical DIprovocIm-1 10mg

Supplier: Cayman Chemical 3317410 MG

ABadrenergic and 5-HT1A receptor antagonist (IC50s 2.8 and 9.9 nM respectively) inhibits isoprenaline-induced adenylate cyclase activity in guinea pig myocardial membranes (Ki 2.4 nM) reduces basal renin activity and blood pressure in spontaneously hypertonic rats decreases isolation-induced aggressive behavior in mice (ED50 56 Umol/kg) and reverses 8-hydroxy-DPAT- and TFMPP-induced reductions in aggression (ED50s 8.1 and 2.1 Umol/kg respectively)
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