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Cayman Chemical DIsuccInImIdyl Suberate 50mg

Supplier: Cayman Chemical 1300850 MG

A competitive purinergic P2Y1 receptor antagonist (Kb 102 nM) selective for P2Y1 over P2Y2 P2Y4 P2Y6 P2Y12 and P2Y13 as well as P2X1-4 receptors at 10 UM reduces 2-MeSADP-induced PLC activity (IC50 331 nM in turkey erythrocyte membranes) inhibits ADP-induced platelet shape change and aggregation in washed isolated human platelets at 10 UM prolongs the length of tail bleeding time in mice as well as decreases platelet thrombus formation in a mouse model of iron chloride-induced arterial thrombosis at 50 mg/kg
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