Disuccinimidyl suberate, 97%

Description

CAS: 68528-80-3 | C16H20N2O8 | 368.342 g/mol

Disuccinimidyl suberate is a homobifunctional amine-reactive crosslinker. It is usually coupled to molecules containing primary amines via amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates an 8-atom spacer arm.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Disuccinimidyl suberate is a homobifunctional amine-reactive crosslinker. It is usually coupled to molecules containing primary amines via amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates an 8-atom spacer arm.

Solubility
Insoluble in water. Soluble in chloroform: 50 mg/mL.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 68528-80-3
• Molecular Formula: C16H20N2O8
• Molecular Weight (g/mol): 368.342
• MDL Number: MFCD00049059
• InChI Key: ZWIBGKZDAWNIFC-UHFFFAOYSA-N
• Synonym: disuccinimidyl suberate, bis 2,5-dioxopyrrolidin-1-yl octanedioate, suberic acid bis n-hydroxysuccinimide ester, di n-succinimidyl suberate, bicl100, 2,5-pyrrolidinedione, 1,1'-1,8-dioxo-1,8-octanediyl bis oxy bis, nhs-sa, disuccinimidylsuberate, dsis, n-hydroxysuccinimide suberic acid ester
• PubChem CID: 100658
• IUPAC Name: bis(2,5-dioxopyrrolidin-1-yl) octanedioate
• SMILES: C1CC(=O)N(C1=O)OC(=O)CCCCCCC(=O)ON2C(=O)CCC2=O

• Melting Point: 166°C to 170°C
• Quantity: 500 mg
• Solubility Information: Insoluble in water. Soluble in chloroform: 50mg/mL.
• Formula Weight: 368.34
• Percent Purity: 97%
• Chemical Name or Material: Disuccinimidyl suberate

Safety and Handling

Hazard Category	H315-H319-H335
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only