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Medchemexpress LLC Divarasib adipate | 2762240-36-6 | 99.2% | C35H42ClF4N7O6 | 25 MG
Supplier: Medchemexpress LLC 25MGHY145928B
Divarasib adipate (GDC-6036 adipate) is an orally bioavailable, highly potent, and selective KRAS G12C inhibitor with an IC50 of less than 0.01 μM. It functions by covalently binding to the switch II (SW-II) pocket of KRAS G12C, which irreversibly locks it in an inactive GDP-bound state.
- Orally bioavailable
- Highly potent and selective KRAS G12C inhibitor
- Covalently binds to the switch II (SW-II) pocket of KRAS G12C
- Irreversibly locks KRAS G12C in the inactive GDP-bound state
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