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Medchemexpress LLC (-)-Dizocilpine (maleate) | 121917-57-5 | C20H19NO4 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY15084A100MG

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(-)-Dizocilpine maleate is a less active (-)-enantiomer of Dizocilpine. It functions as a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with a Ki of 211.7 nM and exhibits antidepressant effects.

  • Less active (-)-enantiomer of Dizocilpine.
  • Functions as a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with a Ki of 211.7 nM.
  • Exhibits antidepressant effects.
  • Significantly inhibits the uptake of norepinephrine, dopamine, and serotonin monoamine transporters in HEK cells in a dose-dependent manner.
  • Induces rapid antidepressant effects in the social defeat stress model in male adult C57BL/6 mice at a dosage of 0.1 mg/kg via intraperitoneal injection.

Catalog No. 50-003-74837


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