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Cayman Chemical DL-3 4-Dihydroxyphenyl glycol

Supplier: Cayman Chemical 117081 MG

A selective JAK2 inhibitor that blocks signaling (IC50 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 60 nM) displays good pharmacokinetics in vivo inhibits STAT3 and STAT5 activation in vivo and suppresses tumorigenesis in mouse xenografts harboring constitutive STAT3 activity
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