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Apexbio Technology LLC DL-Mevalonolactone 674-26-0 250mg
Supplier: Apexbio Technology LLC BA7450250
DL-Mevalonolactone (CAS 674-26-0) is the -lactone form of mevalonic acid serving as an intermediate in the mevalonate pathway This small molecule exhibits oral bioactivity in models of HMG-CoA reductase (HMGCR) mutations and statin-induced myopathy In preclinical studies DL-Mevalonolactone has been shown to induce inflammatory and oxidative stress responses decrease mitochondrial membrane potential and promote mitochondrial swelling It is utilized in research to investigate the biochemical consequences of mevalonate pathway modulation and mitochondrial dysfunction as well as the molecular mechanisms underlying statin-related muscle toxicity
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