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Cayman Chemical DLIn-KC2-DMA 5mg
SDP

Supplier:  Cayman Chemical 343635 MG

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A histamine H1 and PAF receptor antagonist binds to rabbit platelet membranes and guinea pig cerebellum membranes (apparent Kis 0.55 and 0.1 UM respectively in radioligand binding assays) inhibits histamine-induced contraction of isolated guinea pig ileum (pA2 9.29) and PAF-induced platelet aggregation in washed rabbit platelets (pA2 6.68) prevents histamine- or PAF-induced hypotension in rats (ID50s 1.4 and 0.44 mg/kg respectively) reverses histamine- or PAF-induced bronchoconstriction in guinea pigs (ID50s 113 and 9.6 mg/kg respectively)

Catalog No. 50-294-9051


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