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AdipoGen anti-DLL4 (human), mAb (DL86-3AG) (100 µg)
Supplier: AdipoGen AG20A0080C100
Monoclonal Antibody. Recognizes human DLL4. Isotype: Mouse IgG1kappa. Clone: DL86-3AG. Applications: ELISA, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
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