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Cayman Chemical DLthreoHydroxyaspartIc Ac 50mg
SDP

Supplier:  Cayman Chemical 3527450 MG

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An EAAT inhibitor; inhibits glutamate uptake in COS-1 cells expressing human EAAT1 or EAAT2 (IC50s = 96 and 31 µM, respectively); inhibits inward currents induced by L-aspartate in EAAT4-expressing Xenopus oocytes (Ki = 0.6 µM) and by L-glutamate in EAAT5-expressing oocytes (Ki = 2.5 µM) voltage-clamped at -60 mV; intrathecal administration (7.5 and 15 UG/animal) reduces the number of flinches and shakes in the second phase of the formalin test in rats

Catalog No. 50-291-3470


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