Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000201966

Medchemexpress LLC DM4-SMe | 796073-68-2 | MFCD28400104 | 100.0% | 826.46 | C39H56ClN3O10S2 | 5 MG
SDP

Catalog No. 5000201966
Encompass_Preferred

DM4-SMe is a tubulin-inhibiting cytotoxic metabolite used in antibody-drug conjugate (ADC) research and ADC metabolism studies. It is a metabolite of antibody-maytansin conjugates (AMCs), can be linked to antibodies via disulfide or thioether bonds, and is reported to be oxidized and detoxified by human liver microsomes. DM4-SMe inhibits KB cells with an IC50 of 0.026 nM.

  • Used as an ADC payload and metabolite for research applications.
  • Acts as a microtubule/tubulin inhibitor.
  • Reported KB cell IC50 of 0.026 nM.
  • Available in small research pack sizes, including 5 mg.
  • For research use only; not for human or clinical use.

Catalog No. 50-002-01966 Supplier Medchemexpress LLC Supplier No. HY1300825MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

DM4-SMe is a tubulin-inhibiting cytotoxic metabolite used in antibody-drug conjugate (ADC) research and ADC metabolism studies. It is a metabolite of antibody-maytansin conjugates (AMCs), can be linked to antibodies via disulfide or thioether bonds, and is reported to be oxidized and detoxified by human liver microsomes. DM4-SMe inhibits KB cells with an IC50 of 0.026 nM.

  • Used as an ADC payload and metabolite for research applications.
  • Acts as a microtubule/tubulin inhibitor.
  • Reported KB cell IC50 of 0.026 nM.
  • Available in small research pack sizes, including 5 mg.
  • For research use only; not for human or clinical use.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.