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Medchemexpress LLC DM4-SMe | 796073-68-2 | MFCD28400104 | 100.0% | 826.46 | C39H56ClN3O10S2 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1300825MG

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DM4-SMe is a tubulin-inhibiting cytotoxic metabolite used in antibody-drug conjugate (ADC) research and ADC metabolism studies. It is a metabolite of antibody-maytansin conjugates (AMCs), can be linked to antibodies via disulfide or thioether bonds, and is reported to be oxidized and detoxified by human liver microsomes. DM4-SMe inhibits KB cells with an IC50 of 0.026 nM.

  • Used as an ADC payload and metabolite for research applications.
  • Acts as a microtubule/tubulin inhibitor.
  • Reported KB cell IC50 of 0.026 nM.
  • Available in small research pack sizes, including 5 mg.
  • For research use only; not for human or clinical use.

Catalog No. 50-002-01966


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