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Cayman Chemical DMABA-d6 NHS ester 10mg
SDP

Supplier:  Cayman Chemical 1121810 MG

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A CB2 receptor agonist selective for CB2 over CB1 (Kis 7 1 and 580 nM) considered a protean agonist because it has neutral antagonist and partial agonist activity depending on the assay utilized acts in a species-dependent manner in vitro acting as an agonist at human CB2 receptors (EC50 190 nM) but an inverse agonist at rat and mouse CB2 receptors (EC50s 216 and 463 nM respectively) produces antinociception to thermal stimuli in rat hindpaw neuroprotective preventing Gp120-induced apoptosis in vitro and increasing survival and differentiation of neural progenitor cells increases hippocampal neurogenesis in GFAP/Gp120 transgenic mice when administered at a dose of 10 mg/kg daily for ten days delays motor impairment in a murine model of ALS

Catalog No. 50-295-1622


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