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Cayman Chemical DmyoInosItol phsphat Scre 50uL
SDP

Supplier:  Cayman Chemical 900389550 UL

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An inhibitor of wild-type and mutant EGFR (IC50s 1.07 0.46 0.13 0.26 and 0.19 nM for wild-type EGFR EGFRd746-750/T790M/C797S EGFRL858R/T790M/C797S EGFRd746-750/T790M and EGFRL858R/T790M respectively) inhibits the proliferation of wild-type EGFR-expressing A431 EGFRd746-750/T790M/C797S-expressing Ba/F3 EGFRd746-750/T790M/C797S-expressing H1975 and EGFRd746-750-expressing PC-9 cells (IC50s 147 26.8 163 and 45 nM respectively) reduces tumor growth in triple mutant EGFR mouse xenograft models

Catalog No. 50-289-2841


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