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Medchemexpress LLC DNA2 inhibitor C5 | 35973-25-2 | 98.5% | 10 MG
SDP

Supplier:  Medchemexpress LLC HY12872910MG

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DNA2 inhibitor C5 is a potent, competitive, and specific DNA2 nuclease inhibitor with an IC50 of 20 μM. It inhibits the nuclease, DNA-dependent ATPase, helicase, and DNA-binding activities of DNA2. This product can be used in breast cancer and colorectal cancer research. It is for research use only and not sold to patients.

  • Potent, competitive, and specific DNA2 nuclease inhibitor
  • Inhibits nuclease, DNA-dependent ATPase, helicase, and DNA-binding activities of DNA2
  • Useful in breast cancer and colorectal cancer research
  • Exhibits strong synergistic effect in inhibiting MCF7 cell survival with MK4827
  • Shows synthetic lethality with deficiencies in FEN1, EXO1, or MRE11 genes in mouse model
  • IC50 of 20 μM for DNA2 nuclease

Catalog No. 50-003-40446


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