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Cayman Chemical DNARNA OxIdatIve DamageClo 480
Supplier: Cayman Chemical 501130480 SOLID
A flavonoid glucoside with diverse biological activities scavenges DPPH radicals in a cell-free assay (IC50 139.62 Ug/ml) inhibits the proliferation of Raji lymphoblasts but not isolated human PBMCs at 20 UM induces apoptosis decreases levels of COX-2 VEGF PI3K and phosphorylated Akt and increases levels of PTEN in SMMC-7721 cells at 1.63 UM reduces tumor weight and volume and increases survival in a Raji mouse xenograft model at 30 mg/kg per day decreases plasma levels of triglycerides total cholesterol LDL ALT AST TNF-a and IL-6 and reduces liver levels of TNF-a and IL-6 in rats fed a high-fat diet at 200 mg/kg per day
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