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Cayman Chemical DocosapentaenoIc AcId 100mg
Supplier: Cayman Chemical 90165100 MG
A synthetic peptide and peptide dual agonist of GLP-1R and GCGR increases cAMP accumulation in CHO cells overexpressing recombinant human GLP-1R or GCGR (EC50s 6.9 and 10.2 pM respectively) reduces food intake and fat mass as well as improves glucose tolerance in DIO mice at 10 nmol/kg reduces food intake and body weight in wild-type but not Glp1r knockout mice reduces the hepatic lipid percentage in both wild-type and Glp1r knockout mice reduces total hepatic triglycerides diglycerides cholesterol and free fatty acids as well as reduces hepatic inflammation and fibrosis in an ob/ob mouse model of NASH induced by a high-trans fat high-fructose and high-cholesterol diet at 10 nmol/kg
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