Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000354374

Medchemexpress LLC Dosimertinib-d5 mesylate | 2403760-72-3 | 99.4% | C29H32D5N7O5S | 1 MG
SDP

Catalog No. 5000354374
Encompass_Preferred

Dosimertinib-d5 (mesylate) is a potent, orally active Epidermal Growth Factor Receptor (EGFR) inhibitor. It decreases the expression of p-EGFR and p-ERK protein levels, demonstrating antiproliferative and anti-tumor activity. It has potential for research into non-small-cell lung cancer (NSCLC).

  • Potent and orally active EGFR inhibitor.
  • Decreases p-EGFR and p-ERK protein levels.
  • Antiproliferative and anti-tumor activity.
  • Suitable for use as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
  • Decreases p-EGFR and p-ERK protein levels in A431 and H1975 cells in a dose-dependent manner.
  • Shows anti-tumor activity in BALB/c nude mice with H1975 xenograft model.
  • Soluble in DMSO at 100 mg/mL (166.46 mM), requiring ultrasonic and warming to 80°C.

Catalog No. 50-003-54374 Supplier Medchemexpress LLC Supplier No. HY142283AS1MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

Dosimertinib-d5 (mesylate) is a potent, orally active Epidermal Growth Factor Receptor (EGFR) inhibitor. It decreases the expression of p-EGFR and p-ERK protein levels, demonstrating antiproliferative and anti-tumor activity. It has potential for research into non-small-cell lung cancer (NSCLC).

  • Potent and orally active EGFR inhibitor.
  • Decreases p-EGFR and p-ERK protein levels.
  • Antiproliferative and anti-tumor activity.
  • Suitable for use as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
  • Decreases p-EGFR and p-ERK protein levels in A431 and H1975 cells in a dose-dependent manner.
  • Shows anti-tumor activity in BALB/c nude mice with H1975 xenograft model.
  • Soluble in DMSO at 100 mg/mL (166.46 mM), requiring ultrasonic and warming to 80°C.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.