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Supplier:  Kyfora Bio 1447625


DOTMA Chloride N N N-trimethyl-2 3-bis[(9Z)-9-octadecen-1-yloxy]-1-propanaminium chloride is a proven reagent for highly efficient liposomal transfection of DNA RNA oligonucleotides and other negatively charged large biomolecules. Several other techniques of introducing genetic material into cells suffer from inadequate reproducibility cytotoxicity inconvenient processes and low transfection efficiency. DOTMA Cl avoids these drawbacks and works by encapsulating the negatively charged DNA within spontaneously formed liposomal vesicles. These DOTMA/DNA complexes fuse with cell membranes and insert DNA directly into the cytoplasm. This mechanism of action ensures transfection occurs efficiently and with little cytotoxicity. APPLICATIONS Transfection of mammalian cells with DNA RNA and oligonucleotides

Catalog No. 50-255-9846

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