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Cayman Chemical DotrIacontnoIc ACD methyl10mg

Supplier: Cayman Chemical 2672810 MG

An ectoparasiticide and antipruritic agent blocks mouse TRPV4 channel expressed in HEK293 cells in a calcium-dependent manner (IC50s 223.5 and 15.5 M in buffer containing 0 and 2 mM calcium respectively) inhibits scratching behavior in mice induced by the TRPV4 agonist GSK1016790A topical application inhibits scratching behavior in mice induced by histamine serotonin and the PAR2 agonist SLIGRL-NH2 (0.025 g of a 10 ointment)
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