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Selleck Chemical LLC Dovitinib (TKI-258) 10mg 405169-16-6 CHIR-258
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Supplier:  Selleck Chemical LLC S101810MG

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Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. Phase 4. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

Catalog No. 50-619-6


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