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Apexbio Technology LLC Doxapram HCl 7081-53-0 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A84195.1
Doxapram hydrochloride (CAS 7081-53-0) is a respiratory stimulant that exerts its biological effects primarily through inhibition of two-pore domain potassium (K2P) channels specifically the TASK-1 and TASK-3 subtypes as well as their heterodimers Electrophysiological studies demonstrate that Doxapram HCl suppresses the activity of these channels with varying potency depending on concentration and channel subtype This selective TASK channel blockade makes Doxapram HCl a useful research tool for investigating the physiological and pathophysiological roles of TASK channels in respiratory regulation central nervous system function and oxygen-sensing mechanisms
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