Thermo Scientific Chemicals Doxycycline hyclate, 98%

Description

Doxycycline hyclate, Doryx, CAS # 24390-14-5, is the hyclate salt form of the broad-spectrum antibiotic known as doxycycline.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Doxycycline hyclate is a broad-spectrum bacteriostatic antibiotic of the tetracycline class
• Doxycycline inhibits bacterial growth by preventing polypeptide formation via inhibition of at least one ribosomal subunit
• Known to reversibly bind the 30S ribosomal subunit and inhibit formation of the aminoacyl-tRNA/mRNA-ribosome complex
• Inhibits matrix metalloproteinases in many microorganisms

Applications

• Effective against the bacteria that cause Lyme disease, chlamydia, rickettsia and mycoplasma; suitable for antibiotic resistance testing and study of cellular mechanisms
• Intended for laboratory use only

Specifications

Chemical Identifiers

• CAS: 24390-14-5
• Molecular Formula: ₀·5 C₂H₆O
• Molecular Weight (g/mol): 512.94
• InChI Key: ISZOFWGVNMFENH-YDLUHMIOSA-N
• Synonym: doryx, doxycycline hyclate, doxycycline, hydrochloride, hemiethanolate, hemihydrate;
• PubChem CID: 131676157
• IUPAC Name: (4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;ethanol;dihydrate;hydrochloride
• SMILES: CCO.CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.O.Cl

• Infrared Spectrum: Authentic
• Assay Percent Range: 97.5% min. (HPLC)
• Quantity: 5 g
• Merck Index: 15,3488
• Solubility Information: Solubility in water: soluble.
• Formula Weight: 512.94
• Percent Purity: 98%
• Chemical Name or Material: Doxycycline hyclate

Safety and Handling

Hazard Category	GHS Signal Word: Warning
Hazard Statement	GHS H Statement Harmful if swallowed. Suspected of damaging fertility. Suspected of damaging the unborn child. May cause respiratory irritation. Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	GHS P Statement IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and kee
Recommended Storage	Store locked up. Store in a well-ventilated place. Keep container tightly closed.

SDS

RUO – Research Use Only