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  6. J6057922PM

Doxycycline Hyclate, Thermo Scientific Chemicals PROMO

Catalog No. J6057922PM
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100 g

Description

Doxycycline hyclate, Doryx, CAS # 24390-14-5, is the hyclate salt form of the broad-spectrum antibiotic known as doxycycline.

General description

  • Doxycycline hyclate is a broad-spectrum bacteriostatic antibiotic of the tetracycline class
  • Doxycycline inhibits bacterial growth by preventing polypeptide formation via inhibition of at least one ribosomal subunit
  • Known to reversibly bind the 30S ribosomal subunit and inhibit formation of the aminoacyl-tRNA/mRNA-ribosome complex
  • Inhibits matrix metalloproteinases in many microorganisms

Applications

  • Effective against the bacteria that cause Lyme disease, chlamydia, rickettsia and mycoplasma; suitable for antibiotic resistance testing and study of cellular mechanisms
  • Intended for laboratory use only
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 24390-14-5
Molecular Formula C26H41ClN2O12
Molecular Weight (g/mol) 609.066 g/mol
MDL Number MFCD07357237
InChI Key ISZOFWGVNMFENH-YDLUHMIOSA-N
Synonym Hydramycin; Doxycycline Hydrochloride Hemiethanolate Hemihydrate
PubChem CID 131676157
IUPAC Name (4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;ethanol;dihydrate;hydrochloride
SMILES CCO.CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.O.Cl

Specifications

Type Doxycycline Hyclate
Physical Form Powder
Color Yellow
Quantity 100 g
Merck Index 14,3440
Solubility Information Soluble in Water to 50mg/ml; May require warming;Soluble in Water,methanol; Sparingly soluble in ethanol; Insoluble in chloroform and ether.
Formula Weight 512.94 g/mol (503.94 g/mol Anhydrous)
Chemical Name or Material Doxycycline hyclate

Safety and Handling

Hazard Category H302-H315-H319-H335-H361fd
Hazard Statement GHS H Statement: H302-H315-H319-H335. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement P201-P202-P261-P264b-P270-P271-P280i-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
RTECSNumber QI8925000
TSCA No
Recommended Storage Keep Cold

RUO – Research Use Only

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