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Doxycycline Hydrochloride, MP Biomedicals™

Catalog No. MP219504410 Shop All MP Biomedicals, Inc Products
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Catalog No. MP219504410 Supplier MP Biomedicals, Inc Supplier No. 0219504410
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Description

More active biologically than the corresponding 6b-epimer hydrochloride. Doxycycline Hydrochloride, MP Biomedicals is a broad spectrum antibiotic effective against gram-positive and gram-negative bacteria. It is a derivative of oxytetracycline used to inh

Doxycycline Hydrochloride is a synthetic oxytetracycline derivative and is a member of the tetracycline antibiotics group. It shows antiprotozoal properties and is a potent inhibitor of MMPs (matrix metallo-proteinases), such as type 1 collagenase. It is used to treat a variety of infections and for other biomedical applications.

  • Treats chronic prostatitis, sinusitis, pelvic inflammatory disease, acne, rosacea, and rickettsial infections
  • Inhibits the inflammatory response of Lyme disease
  • Used in prophylaxis of anthrax (caused by Bacillus anthracis)
  • Effective against Yersinia pestis
  • Inhibits collagen synthesis
  • Used in studies on wound healing and tissue remodeling
  • Eliminates Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs
  • Eliminates Ixodes scapularis ticks
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 10592-13-9
Molecular Formula C22H25ClN2O8
Molecular Weight (g/mol) 480.90
MDL Number MFCD03427564
InChI Key VLUQVUWDECWBTL-UQVCFKGQSA-N
Synonym Biocamycin, Doxigalumicina, Doxycycline hyclate, Doxy-II, Midoxin, Novadox, Retens, Tetradox, Vibradox, Hydramycin, 2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride
PubChem CID 54706018
IUPAC Name [(1S,4aR,11R,11aR,12S,12aR)-3-carbamoyl-4,4a,6,7,12-pentahydroxy-11-methyl-2,5-dioxo-11,11a,12,12a-tetrahydro-1H-tetracen-1-yl]-dimethylazanium;chloride
SMILES [Cl-].C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H]([NH+](C)C)C(=O)\C(=C(/N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12

Specifications

Physical Form Powder
Concentration Working Concentration: It is typically used at a concentration of 20ug/mL and is stable in media at 37°C for approximately 5 days.
Quantity 10 g
Solubility Information Soluble in water (10mg/mL, clear, yellowish to yellowish-green solution) and DMSO (50mg/mL).
Formula Weight 480.9

Safety and Handling

Recommended Storage Store at 4°C, desiccate, protect from light.
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