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Medchemexpress LLC DPC-681 | 284661-68-3 | 99.7% | 669.85 | 10 MM * 1 ML
Supplier: Medchemexpress LLC HY1940010MM/1ML
DPC-681 is a potent and selective inhibitor of HIV protease with IC90s for wild-type HIV-1 of 4 to 40 nM.
- Potent and selective inhibitor of HIV protease.
- Effective against wild-type HIV-1.
- Shows no loss in potency toward recombinant mutant HIVs with the D30N mutation.
- Exhibits a fivefold or smaller loss in potency toward mutant variants with three to five amino acid substitutions.
- Hepatic extraction can be saturated in dogs, leading to increased bioavailability at higher doses.
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