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Cayman Chemical dPE-PEG 2000-Mnose 5mg
Supplier: Cayman Chemical 389145 MG
An antagonist of CXCR4 (IC50s 0.02-0.13 Ug/ml) selective for CXCR4 over CXCR1-3 and CXCR5-9 (IC50s 25 Ug/ml) decreases infectious virus content in the supernatant of Jurkat cells chronically infected with HIV-1(IIIB) (EC50 ~0.02 Ug/ml) mobilizes murine and human hematopoietic stem and murine long-term repopulating cells for transplantation increases T cell trafficking in mouse blood spleen and central nervous system decreases the number of 4T1 murine mammary carcinoma cells in the lung in a mouse model of lung metastasis at 1.25 mg/kg twice per day
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