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Medchemexpress LLC DRB18 | 2863686-81-9 | 99.6% | C22H23ClN2O2 | 50 MG
Supplier: Medchemexpress LLC HY14596350MG
DRB18 is a potent pan-class GLUT inhibitor that modifies energy-related metabolism in A549 cells by altering metabolite abundance in glucose-related pathways. This can result in G1/S phase arrest, increased oxidative stress, and necrotic cell death. It has demonstrated anti-tumor activity.
- Potent pan-class GLUT inhibitor
- Modifies energy-related metabolism in A549 cells
- Leads to G1/S phase arrest
- Increases oxidative stress
- Causes necrotic cell death
- Demonstrates anti-tumor activity
- Reduces glucose uptake in HEK293 cell lines
- Inhibits tumor volume and weight in xenografted tumors
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