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Cayman Chemical DrondaronhydrochlorIde 100mg
Supplier: Cayman Chemical 9000543100 MG
An antiarrhythmic agent; inhibits muscarinic acetylcholine receptor-dependent potassium currents induced by carbachol or intracellular loading of GTPγS in single cells isolated from guinea pig atria (IC50s = 0.1 and 1 µM, respectively); reduces sinus frequency and prolongs APD in isolated rabbit ventricular myocardium at 50 and 100 mg/kg; increases atrial APD and the AERP in a dog model of atrial fibrillation
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