Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Dronedarone Hydrochloride | 141625-93-6 | 99.99% | C31H45ClN2O5S | 200 MG
Supplier: Medchemexpress LLC HY75839200MG
Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that acts as a multichannel blocker for atrial fibrillation by inhibiting Na+, K+, and Ca2+ currents.
- Inhibits Na+, K+, and Ca2+ currents
- Acts as a multichannel blocker for atrial fibrillation
- Potently inhibits acetylcholine-activated K+ current
- Blocks IKr (IC50=3 μM) and ICa-L (IC50=0.18 μM) under whole-cell patch clamp
- Exhibits state-dependent inhibition of fast Na+ channel current
- Reduces incidence of ventricular fibrillation in rats
- Inhibits carotid artery thrombus formation in vivo
- Impairs thrombin- and collagen-induced platelet aggregation
- Reduces expression of plasminogen activator inhibitor-1 (PAI1)
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?