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Medchemexpress LLC DRP1i27 dihydrochloride | C20H28Cl2N6O | 5 MG
Supplier: Medchemexpress LLC HY152086A5MG
DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). It binds to the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. This compound targets Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.
- Directly binds to and inhibits the GTPase activity of human Drp1
- Increases cellular networks of mitochondria in human and mouse fibroblasts
- Protective effects against simulated ischemia-reperfusion injury
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