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Medchemexpress LLC DS18561882 | 2227149-22-4 | 99.9% | 100 MG
SDP

Catalog No. 5000340869
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DS18561882 is a highly potent, isozyme-selective methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with an IC50 value of 0.0063 μM. It also demonstrates an inhibitory effect on MTHFD1 (IC50=0.57 μM) and exhibits a good oral pharmacokinetic profile. This compound, with a molecular weight of 608.63 and formula C28H31F3N4O6S, appears as a white to yellow solid. It has potential anti-tumor activity by inhibiting tumor growth in a dose-dependent manner.

  • Inhibits MTHFD2 and MTHFD1
  • Reduces cell viability in MDA-MB-231 cell lines
  • Inhibits tumor growth in mouse models
  • Used to study cisplatin-mediated apoptotic cell death
  • Applied in histological analysis to alleviate pulmonary fibrosis
  • Suitable for assessing HSC numbers and ferroptosis susceptibility

Catalog No. 50-003-40869 Supplier Medchemexpress LLC Supplier No. HY130251100MG
May include imposed supplier surcharges.
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DS18561882 is a highly potent, isozyme-selective methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with an IC50 value of 0.0063 μM. It also demonstrates an inhibitory effect on MTHFD1 (IC50=0.57 μM) and exhibits a good oral pharmacokinetic profile. This compound, with a molecular weight of 608.63 and formula C28H31F3N4O6S, appears as a white to yellow solid. It has potential anti-tumor activity by inhibiting tumor growth in a dose-dependent manner.

  • Inhibits MTHFD2 and MTHFD1
  • Reduces cell viability in MDA-MB-231 cell lines
  • Inhibits tumor growth in mouse models
  • Used to study cisplatin-mediated apoptotic cell death
  • Applied in histological analysis to alleviate pulmonary fibrosis
  • Suitable for assessing HSC numbers and ferroptosis susceptibility

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