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Medchemexpress LLC DSM705 hydrochloride | 2989908-08-7 | 99.6% | C19H20ClF3N6O | 10MG

Supplier: Medchemexpress LLC HY132171A10MG
DSM705 hydrochloride is the hydrochloride salt of DSM705, a pyrrole-based dihydroorotate dehydrogenase (DHODH) inhibitor with oral antimalarial activity. It shows nanomolar potency against Plasmodium DHODH (IC50 ≈95 nM for P. falciparum and ≈52 nM for P. vivax) and activity against Plasmodium parasites, with minimal inhibition of mammalian DHODHs.
- Pyrrole-based DHODH inhibitor with nanomolar potency.
- Orally active antimalarial compound.
- Selective for Plasmodium DHODH over mammalian DHODHs.
- Hydrochloride salt form for improved solubility and handling.
- Available in multiple solid and solution pack sizes for research use.
- Reported purity approximately 99.6%.
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