Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC DSR-141562 | 2007975-22-4 | 99.98% | 414.42 | 1 ML
Supplier: Medchemexpress LLC HY13656910MM/1ML
DSR-141562 is an orally active, selective, brain-penetrant phosphodiesterase 1 (PDE1) inhibitor. It shows preferential selectivity for human PDE1B and inhibits human PDE1A and 1C. This compound is used in the study of positive symptoms, negative symptoms, and cognitive impairments associated with schizophrenia.
- Orally active, selective, brain-penetrant PDE1 inhibitor
- Preferentially selective for human PDE1B, inhibiting human PDE1A and 1C
- Suitable for studying positive, negative, and cognitive symptoms of schizophrenia
- Demonstrates good brain uptake in rats
- Increases cGMP contents in the frontal cortex and striatum
- Reverses methamphetamine-induced locomotor hyperactivity in mice
- Reverses phencyclidine-induced decrease of social interaction time in mice
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?