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Medchemexpress LLC DSR-6434 | 1059070-10-8 | 99.3% | 400.48 | 50 MG
SDP

Catalog No. 5000344243
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DSR-6434 is a potent and selective Toll-like receptor 7 (TLR7) agonist, with EC50s of 7.2 nM and 4.6 nM for human and mice TLR7, respectively. It has a strong antitumor effect. DSR-6434 stimulates reporter gene activity only in HEK293 cells expressing hTLR7 and not in HEK293 cells expressing the structurally similar hTLR8 or hTLR9. In vivo, treatment suppresses lung metastasis significantly.

  • Potent and selective Toll-like receptor 7 (TLR7) agonist.
  • EC50s of 7.2 nM for human TLR7 and 4.6 nM for mice TLR7.
  • Strong antitumor effect.
  • Stimulates reporter gene activity only in HEK293 cells expressing hTLR7.
  • Suppresses lung metastasis significantly in vivo.

Catalog No. 50-003-44243 Supplier Medchemexpress LLC Supplier No. HY11012010MM/1ML
May include imposed supplier surcharges.
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DSR-6434 is a potent and selective Toll-like receptor 7 (TLR7) agonist, with EC50s of 7.2 nM and 4.6 nM for human and mice TLR7, respectively. It has a strong antitumor effect. DSR-6434 stimulates reporter gene activity only in HEK293 cells expressing hTLR7 and not in HEK293 cells expressing the structurally similar hTLR8 or hTLR9. In vivo, treatment suppresses lung metastasis significantly.

  • Potent and selective Toll-like receptor 7 (TLR7) agonist.
  • EC50s of 7.2 nM for human TLR7 and 4.6 nM for mice TLR7.
  • Strong antitumor effect.
  • Stimulates reporter gene activity only in HEK293 cells expressing hTLR7.
  • Suppresses lung metastasis significantly in vivo.

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