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Medchemexpress LLC DTPD-Q | 252950-56-4 | 99.7% | 318.37 | 25 MG
Supplier: Medchemexpress LLC 25MGHY163650
DTPD-Q is a transformation product of the tire additive N,N′-diphenyl-p-phenylenediamine (DTPD). It accumulates and increases ecological risk in the environment.
- Inhibits dynamin 1 (IC50 = 273 μM).
- Reduces clathrin-mediated endocytosis in serum-starved U2OS cells (IC50 = 120 μM).
- Less toxic to the aquatic bacterium V. fischeri than DTPD (EC50 = 1.98 mg/L).
- Increases intestinal permeability and the production of reactive oxygen species (ROS) in C. elegans at concentrations of 1 or 10 μg/ml.
- Detected in roadway runoff water, roadside soils, indoor dust, and consumer products made from recycled tire rubber.
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