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Medchemexpress LLC Duocarmycin DM free base | 1116745-06-2 | MFCD32201125 | 99.7% | 463.96 | C26H26ClN3O3 | 10 MG
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Supplier:  Medchemexpress LLC HY12891510MG

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Duocarmycin DM free base is a DNA minor-groove alkylating cytotoxin used in antibody-drug conjugate (ADC) research and studies of DNA damage and cell-cycle effects. It alkylates adenine in AT-rich sequences and exhibits extremely potent cytotoxicity against cancer cells.

  • dna minor-groove alkylator used as an adc cytotoxin and research payload.
  • cas number 1116745-06-2; molecular formula C26H26ClN3O3; molecular weight 463.96.
  • high solubility in DMSO (50 mg/mL); in vivo formulations achieve ≥2 mg/mL as clear solutions.
  • storage: -20°C protected from light and under nitrogen; in solvent: -80°C up to 6 months, -20°C up to 1 month.
  • available pack sizes include 1 mg, 5 mg, and 10 mg for stock preparation.

Catalog No. 50-002-03476


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