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Medchemexpress LLC DX600 | 478188-26-0 | 99.7% | 3074.33 | 10 MG
SDP

Catalog No. 5000423716
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DX600 is a selective ACE2 specific inhibitor with a KD of 1.3 nM, and it does not cross-react with ACE. It exacerbates diabetes-induced cardiovascular dysfunction and increases cardiac and renal NOX activity.

  • Inhibits rhACE2 activity
  • Decreases NR 8383 cell growth and increases TNF-a and IL-6 content in the supernatant
  • Exacerbates diabetes-induced cardiovascular dysfunction in Streptozotocin-treated diabetic rats
  • Increases thrombus weight in a thrombosis model in rats

Catalog No. 50-004-23716 Supplier Medchemexpress LLC Supplier No. HYP222210MG
May include imposed supplier surcharges.
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DX600 is a selective ACE2 specific inhibitor with a KD of 1.3 nM, and it does not cross-react with ACE. It exacerbates diabetes-induced cardiovascular dysfunction and increases cardiac and renal NOX activity.

  • Inhibits rhACE2 activity
  • Decreases NR 8383 cell growth and increases TNF-a and IL-6 content in the supernatant
  • Exacerbates diabetes-induced cardiovascular dysfunction in Streptozotocin-treated diabetic rats
  • Increases thrombus weight in a thrombosis model in rats

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