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Cayman Chemical Dynarrestin 10MG
SDP

Supplier:  Cayman Chemical 3552710 MG

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A dynein inhibitor; inhibits dynein 1-dependent microtubule gliding (IC50 = 5 µM) and dynein 2-dependent intraflagellar transport in mIMCD-3 cells at 0.125 and 1.25 µM; decreases the number of cells in metaphase, anaphase, or telophase in asynchronous COS-7 cells (IC50 = 6.25 µM); inhibits the proliferation of primary Ptch+/- murine medulloblastoma cells (IC50 = 0.068 µM) and the expression of GLI1 in purmorphamine-stimulated KYSE-180 cells (IC50 = 0.21 µM)

Catalog No. 50-291-3519


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