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Apexbio Technology LLC Dynasore 304448-55-3 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A16055.1
Dynasore is a non-competitive inhibitor targeting dynamin family GTPases including dynamin1 dynamin2 and Drp1 with an IC50 of approximately 15 M Dynamin GTPases mediate membrane fission processes required for endocytosis and intracellular vesicle trafficking through catalyzing GTP hydrolysis Dynasore inhibits dynamin-mediated endocytic pathways by blocking GTPase activity thus preventing vesicle scission during endocytosis In biological research dynasore is frequently used to investigate dynamin-dependent endocytosis in cellular and neuronal models facilitating studies on synaptic vesicle recycling membrane trafficking and signaling dynamics
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