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Abcam Dyngo 4a, Novel, highly potent dynamin inhibitor, 5MG

Supplier:  Abcam AB1206895MG

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Dyngo 4a, Novel, highly potent dynamin inhibitor (IC50 values are 400 nM and 200 nM at dynamin I and II human-recombinant, respectively). Inhibits clathrin-mediated endocytosis (IC50 = 5.5 µM). Dynasore (ab120192) analog. Prevents botulin neurotoxin A (BoNTs) uptake and internalization, and prevents SNAP25 cleavage. Inhibits BoNTs-induced paralysis and delays botulism onset. - Cited in over 75 publications - Purity > 99% - Soluble in DMSO to 100 mM

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. NC0607525


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