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Medchemexpress LLC Dynole 2-24 | 1416313-72-8 | 99.07% | C24H41N3 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14508050MG

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Dynole 2-24 is an indole-based dynamin GTPase inhibitor. It is nontoxic and demonstrates increased potency against dynamin I and II both in vitro and within cells. This compound also exhibits selective inhibition of dynamin I and is an active in-cell inhibitor of clathrin-mediated endocytosis.

  • Indole-based dynamin GTPase inhibitor.
  • Has an IC50 of 0.56 μM for dynamin I.
  • Nontoxic.
  • Shows increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM).
  • Displays 4.4-fold selectivity for dynamin I.
  • Functions as an active in-cell inhibitor of clathrin-mediated endocytosis.

Catalog No. 50-003-56354


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