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Cayman Chemical DYRK1A InhIbItr comp 11 25mg
SDP

Catalog No. 502943418
Encompass_Preferred

A DYRK1A inhibitor (IC50 = 0.4 nM); selective for DYRK1A over DYRK2, Clk1, Clk2, Clk3, Cdk2, and GSK3β (IC50s = 19, 7.1, 9.4, 54, 100, and 94 nM, respectively) but does inhibit DYRK1B (IC50 = 2.7 nM); inhibits DYRK1A-induced increases in tau phosphorylation in a cell-based assay (IC50 = 590 nM)

Catalog No. 50-294-3418 Supplier Cayman Chemical Supplier No. 4171525 MG
May include imposed supplier surcharges.
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A DYRK1A inhibitor (IC50 = 0.4 nM); selective for DYRK1A over DYRK2, Clk1, Clk2, Clk3, Cdk2, and GSK3β (IC50s = 19, 7.1, 9.4, 54, 100, and 94 nM, respectively) but does inhibit DYRK1B (IC50 = 2.7 nM); inhibits DYRK1A-induced increases in tau phosphorylation in a cell-based assay (IC50 = 590 nM)

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