Invitrogen™ Human DYRK1B, GST Tag Recombinant Protein

Catalog No.	Quantity
PV4649	10 μg

Catalog No. PV4649 Supplier Invitrogen™ Supplier No. PV4649

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

DYRK1B is a member of the DYRK family of protein kinases and is proposed to be involved in nuclear functions. Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. DYRK1B encodes the integrin beta 4 subunit, a receptor for the laminins. Mutations in DYRK1B are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for DYRK1B.

Specifications

• Accession Number: Q9Y463
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris with 0.02% Triton X-100, 0.5mM EDTA, 150mM NaCl and no preservative; pH 7.5
• Gene ID (Entrez): 9149
• Molecular Weight (g/mol): 96.7 kDa
• Name: Human DYRK1B, GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: AOMS3; dual specificity tyrosine phosphorylation regulated kinase 1B; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; dual specificity tyrosine-phosphorylation-regulated kinase 1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; DYRK1B; DYRKB; Minibrain-related kinase; Mirk; Mirk protein kinase
• Common Name: DYRK1B
• Gene Symbol: DYRK1B
• Kinase Family: DYRK Kinase Family, DYRKs
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Assay Entry: Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
• Kinase Group: Ser⁄Thr Kinases: CMCG Group
• Shipping Condition: Dry Ice
• System Compatibility: Z'-LYTE™
• Target Entry: DYRK1B
• Target Gene: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1 B
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Full Length
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Signal Transduction

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov