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Medchemexpress LLC DYRKs-IN-1 hydrochloride | 1387090-01-8 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY128758A10MM/1ML

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DYRKs-IN-1 is a potent inhibitor of Dual-specificity tyrosine-phosphorylation-regulated kinases (DYRKs). This compound demonstrates antitumor activity, with IC50 values of 5 nM for DYRK1A and 8 nM for DYRK1B. The hydrochloride salt form offers enhanced water solubility and stability.

  • Potent inhibitor of DYRK1A (IC50: 5 nM) and DYRK1B (IC50: 8 nM)
  • Demonstrates antitumor activity
  • Enhanced water solubility
  • Increased stability
  • Increases cellular potency against human colon tumor cell line SW 620 (EC50: 27 nM)

Catalog No. 50-003-42867


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