Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000061577

Apexbio Technology LLC 3-Deazaneplanocin A (DZNep) hydrochloride 120964-45-6 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC A81825.1

Encompass_Preferred

3-Deazaneplanocin A (DZNep) hydrochloride is a selective inhibitor targeting histone methyltransferase EZH2 exhibiting inhibitory activity with an IC50 range of 0 08-0 24 M Additionally DZNep inhibits S-adenosylhomocysteine hydrolase (SAHH) at a Ki of 50 pM EZH2 acts as a catalytic subunit of polycomb repressive complex 2 (PRC2) participating in modulation of gene expression via histone methylation Research demonstrates that DZNep suppresses EZH2-dependent gene regulation pathways in cancer cells leading to altered expression of cell-cycle and apoptosis-associated genes DZNep is commonly utilized in epigenetic studies of various tumors and metabolic dysfunction models including AML liver fibrosis and lipid accumulation studies

Catalog No. 50-000-61577


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.