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Medchemexpress LLC (E)-1-pyridin-4-yl-3-[7-(trifluoromethyl)quinolin-2-yl]prop-2-en-1-one | 1462249-75-7 | 98.9% | 1 MG
SDP

Supplier:  Medchemexpress LLC HY122031MG

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PFK-158 is a small-molecule PFKFB3 inhibitor used in research to study cancer cell metabolism, autophagy, and apoptosis. It reduces glucose uptake, ATP production, and lactate release in cancer cells and has demonstrated antitumor activity in preclinical studies.

  • Potent PFKFB3 inhibitor (IC50 ≈ 137 nM).
  • Reduces glucose uptake, ATP production, and lactate release in cancer cells.
  • Induces apoptosis and autophagy in tumor cell models.
  • Supplied as a dry powder for laboratory research.
  • Typical purity ~98.9% and molecular weight 328.29 g/mol.

Catalog No. 50-002-30343


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