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Medchemexpress LLC E-7386 | 1799824-08-0 | 99.11% | 725.85 | 50 MG
Supplier: Medchemexpress LLC HY11138610MM/1ML
E-7386 is an orally active CBP/beta-catenin modulator. It can induce T cell infiltration into tumors and enhance the antitumor activity of anti-PD-1 mAb in Wnt1 tumor syngeneic mice models. It demonstrates significant antitumor activity in the Wnt1 model, with clear T cell infiltration into tumors observed in the treatment group compared to the limited infiltration in the vehicle control group.
- Orally active CBP/beta-catenin modulator.
- Induces T cell infiltration into tumors.
- Enhances antitumor activity of anti-PD-1 mAb in Wnt1 tumor syngeneic mice models.
- Shows significant antitumor activity in Wnt1 models.
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