Medchemexpress LLC (E)-9-amino-10-methyl-2-(naphthalen-1-ylmethylene)-1-oxo-1,2,3,4-tetrahydroacridin-10-ium iodide | 2252162-81-3 | 98.1% | C25H21IN2O | 10MG

Supplier:  Medchemexpress LLC HY14166110MG

Aβ/tau aggregation-IN-1 is a small-molecule research inhibitor that reduces aggregation of amyloid-β (Aβ1-42) and tau by preventing β-sheet formation and disrupting aggregate interactions. It demonstrates activity in cell-based tau aggregation assays and has documented physicochemical and storage properties for preclinical use.

• Inhibits aggregation of Aβ1-42 and tau, reducing β-sheet formation.
• Reported KD values ≈160 μM for Aβ1-42 and ≈337 μM for tau.
• Reduces tau aggregation foci at 1 μM in HEK-293T cellular assays.
• High purity (98.1%) suitable for research applications.
• Soluble in DMSO (~33.3 mg/mL); in vivo formulation examples provided.
• Solid storage at 4°C; in solvent store at -80°C for long-term stability.
• For research use only; not for human use.

Catalog No. 50-002-58605