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Medchemexpress LLC (E)-KN-93 phosphate | 1188890-41-6 | 99.85% | 599.03 | 25MG
Supplier: Medchemexpress LLC 25MGHY110140
(E)-KN-93 phosphate is an inhibitor for Ca2+/calmodulin-dependent protein kinase II (CaMK II) with IC50 of 9 μM and 3 μM, for CaMKIIδ monomer and CaMKIIδ dodecamer. It binds competitively with Ca2+/CaM, and disrupts their interaction with CaMK II, thus inhibiting CaMK II activation.
- Inhibits Ca2+/calmodulin-dependent protein kinase II (CaMK II)
- Has an IC50 of 9 μM for CaMKIIδ monomer
- Has an IC50 of 3 μM for CaMKIIδ dodecamer
- Competitively binds with Ca2+/CaM
- Disrupts Ca2+/CaM interaction with CaMK II
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